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Apical and basolateral pools of proteinase-activated receptor-2 direct distinct signaling events in the intestinal epithelium

Studies suggest that there are two distinct pools of proteinase-activated receptor-2 (PAR(2)) present in intestinal epithelial cells: an apical pool accessible from the lumen, and a basolateral pool accessible from the interstitial space and blood. Although introduction of PAR(2) agonists such as 2-...

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Autors principals: Lau, Chang, Lytle, Christian, Straus, Daniel S., DeFea, Kathryn A.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3023197/
https://ncbi.nlm.nih.gov/pubmed/21068362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00162.2010
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