Cystathionine β-synthase and cystathionine γ-lyase double gene transfer ameliorate homocysteine-mediated mesangial inflammation through hydrogen sulfide generation

Elevated level of homocysteine (Hcy) induces chronic inflammation in vascular bed, including glomerulus, and promotes glomerulosclerosis. In this study we investigated in vitro mechanism of Hcy-mediated monocyte chemoattractant protein-1 (MCP-1) and macrophage inflammatory protein-2 (MIP-2) inductio...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Sen, Utpal, Givvimani, Srikanth, Abe, Oluwasegun A., Lederer, Eleanor D., Tyagi, Suresh C.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Physiological Society 2011
Pynciau:
Vascular Biology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3023186/
https://ncbi.nlm.nih.gov/pubmed/20943958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00143.2010
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