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Clustering of Lynch syndrome malignancies with no evidence for a role of DNA Mismatch Repair
OBJECTIVES: We ascertained a large kindred with an excess of Lynch syndrome-associated cancers. Our objective was to determine if a defect in one of the DNA mismatch repair (DMMR) genes was the probable cause of cancer susceptibility as microsatellite instability (MSI) and immunohistochemical (IHC)...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3023170/ https://ncbi.nlm.nih.gov/pubmed/18022218 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygyno.2007.09.036 |
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