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Leptin-dependent serotonin control of appetite: temporal specificity, transcriptional regulation, and therapeutic implications

Recent evidence indicates that leptin regulates appetite and energy expenditure, at least in part by inhibiting serotonin synthesis and release from brainstem neurons. To demonstrate that this pathway works postnatally, we used a conditional, brainstem-specific mouse CreER(T2) driver to show that le...

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Bibliografiske detaljer
Main Authors: Yadav, Vijay K., Oury, Franck, Tanaka, Kenji, Thomas, Tiffany, Wang, Ying, Cremers, Serge, Hen, Rene, Krust, Andree, Chambon, Pierre, Karsenty, Gerard
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3023132/
https://ncbi.nlm.nih.gov/pubmed/21187319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20101940
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