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Leptin-dependent serotonin control of appetite: temporal specificity, transcriptional regulation, and therapeutic implications

Recent evidence indicates that leptin regulates appetite and energy expenditure, at least in part by inhibiting serotonin synthesis and release from brainstem neurons. To demonstrate that this pathway works postnatally, we used a conditional, brainstem-specific mouse CreER(T2) driver to show that le...

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Detaylı Bibliyografya
Asıl Yazarlar: Yadav, Vijay K., Oury, Franck, Tanaka, Kenji, Thomas, Tiffany, Wang, Ying, Cremers, Serge, Hen, Rene, Krust, Andree, Chambon, Pierre, Karsenty, Gerard
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Rockefeller University Press 2011
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3023132/
https://ncbi.nlm.nih.gov/pubmed/21187319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20101940
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