Microbiota-induced tertiary lymphoid tissues aggravate inflammatory disease in the absence of RORγt and LTi cells

The programmed development of lymph nodes and Peyer’s patches during ontogeny requires lymphoid tissue inducer (LTi) cells that express the nuclear hormone receptor RORγt. After birth, LTi cells in the intestine cluster into cryptopatches, the precursors of isolated lymphoid follicles (ILFs), which...

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Autores principales: Lochner, Matthias, Ohnmacht, Caspar, Presley, Laura, Bruhns, Pierre, Si-Tahar, Mustapha, Sawa, Shinichiro, Eberl, Gérard
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2011
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3023125/
https://ncbi.nlm.nih.gov/pubmed/21173107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20100052
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