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Synthesis of Globin Chains in Sickle β-Thalassemia

In five patients with sickle β-thalassemia there was balanced α- and β-globin synthesis in the bone marrow and decreased total β-chain synthesis relative to that of α-chain in the peripheral blood. These findings are similar to those in patients with simple β-thalassemia trait. Despite a range of he...

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Bibliographic Details
Published in:J Clin Invest
Main Authors: Gill, Frances M., Schwartz, Elias
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 1973
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC302309/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4685090/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI107232
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