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Identification of Genes Potentially Involved in the Increased Risk of Malignancy in NF1-Microdeleted Patients

Patients with NF1 microdeletion develop more neurofibromas at a younger age, and have an increased risk of malignant peripheral nerve sheath tumors (MPNSTs). We postulated that the increased risk of malignancy could be due to inactivation, in addition to NF1, of a second tumor suppressor gene locate...

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Hlavní autoři: Pasmant, Eric, Masliah-Planchon, Julien, Lévy, Pascale, Laurendeau, Ingrid, Ortonne, Nicolas, Parfait, Béatrice, Valeyrie-Allanore, Laurence, Leroy, Karen, Wolkenstein, Pierre, Vidaud, Michel, Vidaud, Dominique, Bièche, Ivan
Médium: Artigo
Jazyk:Inglês
Vydáno: ScholarOne 2011
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3022985/
https://ncbi.nlm.nih.gov/pubmed/20844836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2010.00079
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