MicroRNAome profiling in benign and malignant neurofibromatosis type 1-associated nerve sheath tumors: evidences of PTEN pathway alterations in early NF1 tumorigenesis

BACKGROUND: Neurofibromatosis type 1 (NF1) is a common dominant tumor predisposition syndrome affecting 1 in 3,500 individuals. The hallmarks of NF1 are the development of peripheral nerve sheath tumors either benign (dermal and plexiform neurofibromas) or malignant (MPNSTs). RESULTS: To comprehensi...

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Autors principals: Masliah-Planchon, Julien, Pasmant, Eric, Luscan, Armelle, Laurendeau, Ingrid, Ortonne, Nicolas, Hivelin, Mikael, Varin, Jennifer, Valeyrie-Allanore, Laurence, Dumaine, Valérie, Lantieri, Laurent, Leroy, Karen, Parfait, Béatrice, Wolkenstein, Pierre, Vidaud, Michel, Vidaud, Dominique, Bièche, Ivan
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3744175/
https://ncbi.nlm.nih.gov/pubmed/23848554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-14-473
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