siRNA-mediated Downregulation of MMP-9 and uPAR in Combination with Radiation Induces G2/M Cell Cycle Arrest in Medulloblastoma

Our previous work and that of other investigators strongly suggest a relationship between the upregulation of MMP-9 and uPAR and tumor angiogenesis and metastasis. In this study, we evaluated the role of MMP-9 and uPAR in medulloblastoma cancer cell resistance to ionizing irradiation (IR) and tested...

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Bibliografiset tiedot
Päätekijät: Ganji, Purnachandra Nagaraju, Nalla, Arun Kumar, Gupta, Reshu, Mohanam, Sanjeeva, Gujrati, Meena, Dinh, Dzung H., Rao, Jasti S.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2010
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3022965/
https://ncbi.nlm.nih.gov/pubmed/21148633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-10-0399
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