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iASPP is over-expressed in human non-small cell lung cancer and regulates the proliferation of lung cancer cells through a p53 associated pathway

BACKGROUND: iASPP is a key inhibitor of tumour suppressor p53 and is found to be up-regulated in certain malignant conditions. The present study investigated the expression of iASPP in clinical lung cancer, a leading cancer type in the world, and the biological impact of this molecule on lung cancer...

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Detalhes bibliográficos
Main Authors: Chen, Jinfeng, Xie, Fei, Zhang, Lijian, Jiang, Wen G
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3022889/
https://ncbi.nlm.nih.gov/pubmed/21192816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-10-694
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