Brain 5α-dihydroprogesterone and allopregnanolone synthesis in a mouse model of protracted social isolation

Allopregnanolone (ALLO), is a brain endogenous neurosteroid that binds with high affinity to γ-aminobutyric acid type A (GABA(A)) receptors and positively modulates the action of GABA at these receptors. Unlike ALLO, 5α-dihydroprogesterone (5α-DHP) binds with high affinity to intracellular progester...

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Detalhes bibliográficos
Main Authors: Dong, Erbo, Matsumoto, Kinzo, Uzunova, Veska, Sugaya, Ikuko, Takahata, Hiroki, Nomura, Hiroaki, Watanabe, Hiroshi, Costa, Erminio, Guidotti, Alessandro
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2001
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC30228/
https://ncbi.nlm.nih.gov/pubmed/11226329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.051628598
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