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The protein kinase Mζ network as a bistable switch to store neuronal memory

BACKGROUND: Protein kinase Mζ (PKMζ), the brain-specific, atypical protein kinase C isoform, plays a key role in long-term maintenance of memory. This molecule is essential for long-term potentiation of the neuron and various modalities of learning such as spatial memory and fear conditioning. It is...

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Autori principali: Ogasawara, Hideaki, Kawato, Mitsuo
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3022653/
https://ncbi.nlm.nih.gov/pubmed/21194445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-4-181
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