Mannan-binding lectin regulates dendritic cell maturation and cytokine production induced by lipopolysaccharide

BACKGROUND: Mannan-binding lectin (MBL) is a pattern-recognition molecule present in serum, which is involved in the innate immune defense by activating complement and promoting opsonophagocytosis. Dendritic cells (DCs) are professional antigen presenting cells (APCs) that are crucial for the initia...

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Bibliographic Details
Main Authors: Wang, Mingyong, Zhang, Yani, Chen, Yue, Zhang, Liyun, Lu, Xiao, Chen, Zhengliang
Format: Artigo
Language:Inglês
Published: BioMed Central 2011
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3022617/
https://ncbi.nlm.nih.gov/pubmed/21194488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2172-12-1
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