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Toll-Like Receptor 2 Mediates Proliferation, Survival, NF-κB Translocation, and Cytokine mRNA Expression in LIF-Maintained Mouse Embryonic Stem Cells

Toll-like receptor (TLR) activation is important in immune responses and in differentiation of hematopoietic stem cells. We detected mRNA expression of TLRs 1, 2, 3, 5, and 6, but not TLRs 4, 7, 8, and 9 in murine (m)ESC line E14, and noted high cell surface protein expression of TLR2, but not TLR4,...

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Detalhes bibliográficos
Main Authors: Taylor, Tammi, Kim, Young-June, Ou, Xuan, Derbigny, Wilbert, Broxmeyer, Hal E.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3022339/
https://ncbi.nlm.nih.gov/pubmed/20132051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2009.0484
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