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Androgen Receptor Signalling in Prostate Cancer: The Functional Consequences of Acetylation

The androgen receptor (AR) is a ligand activated transcription factor and member of the steroid hormone receptor (SHR) subfamily of nuclear receptors. In the early stages of prostate carcinogenesis, tumour growth is dependent on androgens, and AR directly mediates these effects by modulating gene ex...

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Autori principali: Lavery, Derek N., Bevan, Charlotte L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi Publishing Corporation 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3022265/
https://ncbi.nlm.nih.gov/pubmed/21274273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/862125
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