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Androgen receptor signaling and mutations in prostate cancer

Normal and neoplastic growth of the prostate gland are dependent on androgen receptor (AR) expression and function. Androgenic activation of the AR, in association with its coregulatory factors, is the classical pathway that leads to transcriptional activity of AR target genes. Alternatively, cytopl...

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Detalhes bibliográficos
Autor principal: Koochekpour, Shahriar
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3006239/
https://ncbi.nlm.nih.gov/pubmed/20711217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aja.2010.89
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