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A dual flip-out mechanism for 5mC recognition by the Arabidopsis SUVH5 SRA domain and its impact on DNA methylation and H3K9 dimethylation in vivo

Cytosine DNA methylation is evolutionarily ancient, and in eukaryotes this epigenetic modification is associated with gene silencing. Proteins with SRA (SET- or RING-associated) methyl-binding domains are required for the establishment and/or maintenance of DNA methylation in both plants and mammals...

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Detalhes bibliográficos
Main Authors: Rajakumara, Eerappa, Law, Julie A., Simanshu, Dhirendra K., Voigt, Philipp, Johnson, Lianna M., Reinberg, Danny, Patel, Dinshaw J., Jacobsen, Steven E.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3022260/
https://ncbi.nlm.nih.gov/pubmed/21245167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1980311
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