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Viral interleukin-6 encoded by rhesus macaque rhadinovirus is associated with lymphoproliferative disorder (LPD)

BACKGROUND: Rhesus macaques (RM) co-infected with simian immunodeficiency virus (SIV) and rhesus macaque rhadinovirus (RRV) develop abnormal cellular proliferations characterized as extra-nodal lymphoma and retroperitoneal fibromatosis (RF). RRV encodes a viral interleukin-6 (vIL-6), much like Kapos...

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Bibliographische Detailangaben
Hauptverfasser: Orzechowska, B.U., Manoharan, M., Sprague, J., Estep, R.D., Axthelm, M.K., Wong, S.W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3022225/
https://ncbi.nlm.nih.gov/pubmed/19863672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-0684.2009.00369.x
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