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The Common Inhaled Anesthetic Isoflurane Increases Aggregation of Huntingtin and Alters Calcium Homeostasis in a Cell Model of Huntington’s Disease
Isoflurane is known to increase β-amyloid aggregation and neuronal damage. We hypothesized that isoflurane will have similar effects on the polyglutamine huntingtin protein, and will cause alterations in intracellular calcium homeostasis. We tested this hypothesis in striatal cells from the expanded...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3022103/ https://ncbi.nlm.nih.gov/pubmed/21059370 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2010.10.032 |
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