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Inhalational Anesthetics Induce Cell Damage by Disruption of Intracellular Calcium Homeostasis with Different Potencies

BACKGROUND: We hypothesized that inhalational anesthetics induced cell damage by causing abnormal calcium release from the endoplasmic reticulum via excessive activation of inositol 1,4,5-trisphosphate (IP(3)) receptors, with isoflurane greater potency than sevoflurane or desflurane. METHODS: We tre...

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Main Authors: Yang, Hui, Liang, Ge, Hawkins, Brian, Madesh, Muniswamy, Pierwola, Andrew, Wei, Huafeng
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2598762/
https://ncbi.nlm.nih.gov/pubmed/18648233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0b013e31817f5c47
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