A reduction in ATP demand and mitochondrial activity with neural differentiation of human embryonic stem cells

Here, we have investigated mitochondrial biology and energy metabolism in human embryonic stem cells (hESCs) and hESC-derived neural stem cells (NSCs). Although stem cells collectively in vivo might be expected to rely primarily on anaerobic glycolysis for ATP supply, to minimise production of react...

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Hlavní autoři: Birket, Matthew J., Orr, Adam L., Gerencser, Akos A., Madden, David T., Vitelli, Cathy, Swistowski, Andrzej, Brand, Martin D., Zeng, Xianmin
Médium: Artigo
Jazyk:Inglês
Vydáno: Company of Biologists 2011
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Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3021997/
https://ncbi.nlm.nih.gov/pubmed/21242311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.072272
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