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Reverse Genetics Modification of Cytomegalovirus Antigenicity and Immunogenicity by CD8 T-Cell Epitope Deletion and Insertion

The advent of cloning herpesviral genomes as bacterial artificial chromosomes (BACs) has made herpesviruses accessible to bacterial genetics and has thus revolutionised their mutagenesis. This opened all possibilities of reverse genetics to ask scientific questions by introducing precisely accurate...

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Bibliografiske detaljer
Main Authors: Lemmermann, Niels A. W., Kropp, Kai A., Seckert, Christof K., Grzimek, Natascha K. A., Reddehase, Matthias J.
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi Publishing Corporation 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3021883/
https://ncbi.nlm.nih.gov/pubmed/21253509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/812742
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