Subthreshold α (2)-Adrenergic Activation Counteracts Glucagon-Like Peptide-1 Potentiation of Glucose-Stimulated Insulin Secretion

The pancreatic β cell harbors α (2)-adrenergic and glucagon-like peptide-1 (GLP-1) receptors on its plasma membrane to sense the corresponding ligands adrenaline/noradrenaline and GLP-1 to govern glucose-stimulated insulin secretion. However, it is not known whether these two signaling systems inter...

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Main Authors: Pan, Minglin, Yang, Guang, Cui, Xiuli, Yang, Shao-Nian
Formato: Artigo
Idioma:Inglês
Publicado: Hindawi Publishing Corporation 2011
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3021849/
https://ncbi.nlm.nih.gov/pubmed/21253359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/604989
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