Selective Acylation Enhances Membrane Charge Sensitivity of the Antimicrobial Peptide Mastoparan-X

The partitioning of the wasp venom peptide mastoparan-X (MPX) into neutral and negatively charged lipid membranes has been compared with two new synthetic analogs of MPX where the N(α)-terminal of MPX was acylated with propanoic acid (PA) and octanoic acid (OA). The acylation caused a considerable c...

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Main Authors: Etzerodt, Thomas, Henriksen, Jonas R., Rasmussen, Palle, Clausen, Mads H., Andresen, Thomas L.
Formato: Artigo
Idioma:Inglês
Publicado: The Biophysical Society 2011
Assuntos:
Membrane
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3021677/
https://ncbi.nlm.nih.gov/pubmed/21244836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.11.040
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