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Role of Antibody and Complement in the Immune Clearance and Destruction of Erythrocytes I. IN VIVO EFFECTS OF IgG AND IgM COMPLEMENT-FIXING SITES

A model which permits evaluation in molecular terms of the role of antibody and of complement in the immune destruction of erythrocytes was established in the guinea pig. IgM and IgG immunoglobulins were isolated from rabbit anti-guinea pig erythrocyte antisera and were used to sensitize (51)Cr-labe...

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Detalles Bibliográficos
Publicado en:J Clin Invest
Main Authors: Schreiber, Aland D., Frank, Michael M.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 1972
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC302163/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4536807/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI106846
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