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Role of Antibody and Complement in the Immune Clearance and Destruction of Erythrocytes I. IN VIVO EFFECTS OF IgG AND IgM COMPLEMENT-FIXING SITES

A model which permits evaluation in molecular terms of the role of antibody and of complement in the immune destruction of erythrocytes was established in the guinea pig. IgM and IgG immunoglobulins were isolated from rabbit anti-guinea pig erythrocyte antisera and were used to sensitize (51)Cr-labe...

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Bibliographic Details
Main Authors: Schreiber, Aland D., Frank, Michael M.
Format: Artigo
Language:Inglês
Published: 1972
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC302163/
https://ncbi.nlm.nih.gov/pubmed/4536807
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