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The Effects of Cyanate In Vitro on Red Blood Cell Metabolism and Function in Sickle Cell Anemia
Cyanate, which is in equilibrium with urea, combines with the α-amino group of the aminoterminal valine of hemoglobin in an irreversible, specific carbamylation reaction. Partial carbamylation (0.72 residues/hemoglobin tetramer) as determined by cyanate-(14)C incorporation or hydantoin analysis dimi...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
1972
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC302162/ https://ncbi.nlm.nih.gov/pubmed/5011101 |
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