The Effects of Cyanate In Vitro on Red Blood Cell Metabolism and Function in Sickle Cell Anemia

Cyanate, which is in equilibrium with urea, combines with the α-amino group of the aminoterminal valine of hemoglobin in an irreversible, specific carbamylation reaction. Partial carbamylation (0.72 residues/hemoglobin tetramer) as determined by cyanate-(14)C incorporation or hydantoin analysis dimi...

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Опубликовано в::	J Clin Invest
Главные авторы:	De Furia, Frank G., Miller, Denis R., Cerami, Anthony, Manning, James M.
Формат:	Artigo
Язык:	Inglês
Опубликовано:	American Society for Clinical Investigation 1972
Предметы:	Articles
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC302162/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/5011101/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI106845
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