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Insulin Reduces Neuronal Excitability by Turning on GABA(A) Channels that Generate Tonic Current

Insulin signaling to the brain is important not only for metabolic homeostasis but also for higher brain functions such as cognition. GABA (γ-aminobutyric acid) decreases neuronal excitability by activating GABA(A) channels that generate phasic and tonic currents. The level of tonic inhibition in ne...

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Detalhes bibliográficos
Main Authors: Jin, Zhe, Jin, Yang, Kumar-Mendu, Suresh, Degerman, Eva, Groop, Leif, Birnir, Bryndis
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3021545/
https://ncbi.nlm.nih.gov/pubmed/21264261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016188
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