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In Intact Islets Interstitial GABA Activates GABA(A) Receptors That Generate Tonic Currents in α-Cells

In the rat islets γ-aminobutyric acid (GABA) is produced by the β-cells and, at least, the α-cells express the GABA(A) receptors (GABA(A) channels). In this study, we examined in intact islets if the interstitial GABA activated the GABA(A) receptors. We used the patch-clamp technique to record whole...

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Detalhes bibliográficos
Main Authors: Jin, Yang, Korol, Sergiy V., Jin, Zhe, Barg, Sebastian, Birnir, Bryndis
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3691163/
https://ncbi.nlm.nih.gov/pubmed/23826240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0067228
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