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In Vivo Demonstration of the Cholesterol Feedback System by Means of a Desmosterol Suppression Technique

This report describes a “desmosterol suppression” technique with which it has been possible to demostrate the operation of the cholesterol negative feedback system in the intact animal. 0.1% triparanol in the diet causes a virtually complete block in the conversion of desmosterol to cholesterol by l...

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Bibliografische gegevens
Gepubliceerd in:J Clin Invest
Hoofdauteurs: Bricker, Lee A., Weis, Hans J., Siperstein, Marvin D.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Clinical Investigation 1972
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC302117/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/5009109/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI106804
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