In Vivo Demonstration of the Cholesterol Feedback System by Means of a Desmosterol Suppression Technique
This report describes a “desmosterol suppression” technique with which it has been possible to demostrate the operation of the cholesterol negative feedback system in the intact animal. 0.1% triparanol in the diet causes a virtually complete block in the conversion of desmosterol to cholesterol by l...
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| Udgivet i: | J Clin Invest |
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| Principais autores: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Clinical Investigation
1972
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC302117/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/5009109/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI106804 |
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