Phase II Study of Neoadjuvant Bevacizumab and Radiation Therapy for Resectable Soft Tissue Sarcomas

PURPOSE: Numerous preclinical studies demonstrate that angiogenesis inhibitors can increase the efficacy of radiation therapy (RT). We sought to examine safety and efficacy of bevacizumab (BV) and RT in soft tissue sarcomas (STS) and explore biomarkers for treatment response. METHODS AND MATERIALS:...

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Huvudupphovsmän: Yoon, Sam S., Duda, Dan G., Karl, Daniel L., Kim, Tae-Min, Kambadakone, Avinash R., Chen, Yen-Lin, Rothrock, Courtney, Rosenberg, Andrew E., Nielsen, G. Petur, Kirsch, David G., Choy, Edwin, Harmon, David C, Hornicek, Francis J., Dreyfuss, Jonathan, Ancukiewicz, Marek, Sahani, Dushyant V., Park, Peter J., Jain, Rakesh K., DeLaney, Thomas F.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2010
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3021107/
https://ncbi.nlm.nih.gov/pubmed/20932656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijrobp.2010.07.024
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