Targeting membrane heat-shock protein 70 (Hsp70) on tumors by cmHsp70.1 antibody

Immunization of mice with a 14-mer peptide TKDNNLLGRFELSG, termed “TKD,” comprising amino acids 450–461 (aa(450–461)) in the C terminus of inducible Hsp70, resulted in the generation of an IgG1 mouse mAb cmHsp70.1. The epitope recognized by cmHsp70.1 mAb, which has been confirmed to be located in th...

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Auteurs principaux: Stangl, Stefan, Gehrmann, Mathias, Riegger, Julia, Kuhs, Kristin, Riederer, Isabelle, Sievert, Wolfgang, Hube, Kathrin, Mocikat, Ralph, Dressel, Ralf, Kremmer, Elisabeth, Pockley, Alan G., Friedrich, Lars, Vigh, Laszlo, Skerra, Arne, Multhoff, Gabriele
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2011
Sujets:
Biological Sciences
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3021082/
https://ncbi.nlm.nih.gov/pubmed/21187371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1016065108
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