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Disease allele-dependent small-molecule sensitivities in blood cells from monogenic diabetes
Even as genetic studies identify alleles that influence human disease susceptibility, it remains challenging to understand their functional significance and how they contribute to disease phenotypes. Here, we describe an approach to translate discoveries from human genetics into functional and thera...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
2011
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3021060/ https://ncbi.nlm.nih.gov/pubmed/21183721 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1016789108 |
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