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Cell Autonomous Requirement of Endocardial Smad4 During Atrioventricular Cushion Development in Mouse Embryos
Atrioventricular (AV) cushions are the precursors of AV septum and valves. In this study, we examined roles of Smad4 during AV cushion development using a conditional gene inactivation approach. We found that endothelial/endocardial inactivation of Smad4 led to the hypocellular AV cushion defect and...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3020975/ https://ncbi.nlm.nih.gov/pubmed/21089072 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvdy.22493 |
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