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Large Proteins Have a Great Tendency to Aggregate but a Low Propensity to Form Amyloid Fibrils
The assembly of soluble proteins into ordered fibrillar aggregates with cross-β structure is an essential event of many human diseases. The polypeptides undergoing aggregation are generally small in size. To explore if the small size is a primary determinant for the formation of amyloids under patho...
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| Auteurs principaux: | , , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Public Library of Science
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3020945/ https://ncbi.nlm.nih.gov/pubmed/21249193 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016075 |
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