HCMV Spread and Cell Tropism are Determined by Distinct Virus Populations

Human cytomegalovirus (HCMV) can infect many different cell types in vivo. Two gH/gL complexes are used for entry into cells. gH/gL/pUL(128,130,131A) shows no selectivity for its host cell, whereas formation of a gH/gL/gO complex only restricts the tropism mainly to fibroblasts. Here, we describe th...

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Hauptverfasser: Scrivano, Laura, Sinzger, Christian, Nitschko, Hans, Koszinowski, Ulrich H., Adler, Barbara
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2011
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3020925/
https://ncbi.nlm.nih.gov/pubmed/21249233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1001256
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