The m74 Gene Product of Murine Cytomegalovirus (MCMV) Is a Functional Homolog of Human CMV gO and Determines the Entry Pathway of MCMV

The glycoprotein gO (UL74) of human cytomegalovirus (HCMV) forms a complex with gH/gL. Virus mutants with a deletion of gO show a defect in secondary envelopment with the consequence that virus spread is restricted to a cell-associated pathway. Here we report that the positional homolog of HCMV gO,...

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Detalhes bibliográficos
Main Authors: Scrivano, Laura, Esterlechner, Jasmina, Mühlbach, Hermine, Ettischer, Nicole, Hagen, Christoph, Grünewald, Kay, Mohr, Christian A., Ruzsics, Zsolt, Koszinowski, Ulrich, Adler, Barbara
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863770/
https://ncbi.nlm.nih.gov/pubmed/20181688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02441-09
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