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Ubiquitin-dependent degradation of HDAC4, a new regulator of random cell motility

HDAC4 (histone deacetylase 4) belongs to class IIa of histone deacetylases, which groups important regulators of gene expression, controlling pleiotropic cellular functions. Here we show that, in addition to the well-defined nuclear/cytoplasmic shuttling, HDAC4 activity is modulated by the ubiquitin...

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Main Authors: Cernotta, Nadia, Clocchiatti, Andrea, Florean, Cristina, Brancolini, Claudio
格式: Artigo
語言:Inglês
出版: The American Society for Cell Biology 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3020922/
https://ncbi.nlm.nih.gov/pubmed/21118993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E10-07-0616
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