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Class IIa HDACs: from important roles in differentiation to possible implications in tumourigenesis

Histone deacetylases (HDACs) are important regulators of gene expression. Specific structural features and distinct regulative mechanisms rationalize the separation of the 18 different human HDACs into four classes. The class II comprises a heterogeneous group of nuclear and cytosolic HDACs involved...

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Détails bibliographiques
Auteurs principaux: Clocchiatti, Andrea, Florean, Cristina, Brancolini, Claudio
Format: Artigo
Langue:Inglês
Publié: Blackwell Publishing Ltd 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3918040/
https://ncbi.nlm.nih.gov/pubmed/21435179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2011.01321.x
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