Monomeric Rhodopsin Is Sufficient for Normal Rhodopsin Kinase (GRK1) Phosphorylation and Arrestin-1 Binding

G-protein-coupled receptor (GPCR) oligomerization has been observed in a wide variety of experimental contexts, but the functional significance of this phenomenon at different stages of the life cycle of class A GPCRs remains to be elucidated. Rhodopsin (Rh), a prototypical class A GPCR of visual tr...

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Hauptverfasser: Bayburt, Timothy H., Vishnivetskiy, Sergey A., McLean, Mark A., Morizumi, Takefumi, Huang, Chih-chin, Tesmer, John J. G., Ernst, Oliver P., Sligar, Stephen G., Gurevich, Vsevolod V.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2011
Schlagworte:
Signal Transduction
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3020750/
https://ncbi.nlm.nih.gov/pubmed/20966068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.151043
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