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Structural Analysis of the Conserved Ubiquitin-binding Motifs (UBMs) of the Translesion Polymerase iota in Complex with Ubiquitin

Ubiquitin-binding domains (UBDs) provide specificity to the ubiquitin system, which is also involved in translesion synthesis (TLS) in eukaryotic cells. Upon DNA damage, the UBDs (UBM domains) of polymerase iota (Pol ι) interact with ubiquitinated proliferating cell nuclear antigen to regulate the i...

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Détails bibliographiques
Auteurs principaux: Burschowsky, Daniel, Rudolf, Fabian, Rabut, Gwénaël, Herrmann, Torsten, Matthias, Peter, Wider, Gerhard
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3020744/
https://ncbi.nlm.nih.gov/pubmed/20929865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.135038
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