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Drosophila Cdk4 is required for normal growth and is dispensable for cell cycle progression

Complexes of D-type cyclins and cdk4 or 6 are thought to govern progression through the G(1) phase of the cell cycle. In Drosophila, single genes for Cyclin D and Cdk4 have been identified, simplifying genetic analysis. Here, we show that Drosophila Cdk4 interacts with Cyclin D and the Rb homolog RB...

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Hlavní autoři: Meyer, Claas A., Jacobs, Henning W., Datar, Sanjeev A., Du, Wei, Edgar, Bruce A., Lehner, Christian F.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2000
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC302073/
https://ncbi.nlm.nih.gov/pubmed/10970847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.17.4533
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