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Requirements of the Engineered Leader Peptide of Nisin for Inducing Modification, Export, and Cleavage

Nisin A is a pentacyclic peptide antibiotic produced by Lactococcus lactis. The leader peptide of prenisin keeps nisin inactive and has a role in inducing NisB- and NisC-catalyzed modifications of the propeptide and NisT-mediated export. The highly specific NisP cleaves off the leader peptide from f...

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Bibliographic Details
Main Authors: Plat, Annechien, Kluskens, Leon D., Kuipers, Anneke, Rink, Rick, Moll, Gert N.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3020565/
https://ncbi.nlm.nih.gov/pubmed/21097596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.01503-10
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