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Engineered Biosynthesis of Gilvocarcin Analogues with Altered Deoxyhexopyranose Moieties
A combinatorial biosynthetic approach was used to interrogate the donor substrate flexibility of GilGT, the glycosyltransferase involved in C-glycosylation during gilvocarcin biosynthesis. Complementation of gilvocarcin mutant Streptomyces lividans TK24 (cosG9B3-U(−)), in which the biosynthesis of t...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3020532/ https://ncbi.nlm.nih.gov/pubmed/21075894 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.01774-10 |
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