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Triphosphate structure of guanylate-binding protein 1 and implications for nucleotide binding and GTPase mechanism
The interferon-γ-induced guanylate-binding protein 1 (GBP1) belongs to a special class of large GTP- binding proteins of 60–100 kDa with unique characteristics. Here we present the structure of human GBP1 in complex with the non-hydrolysable GTP analogue GppNHp. Basic features of guanine nucleotide...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC302049/ https://ncbi.nlm.nih.gov/pubmed/10970849 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.17.4555 |
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