LysGH15, a Novel Bacteriophage Lysin, Protects a Murine Bacteremia Model Efficiently against Lethal Methicillin-Resistant Staphylococcus aureus Infection

Phage-coded lysin is an enzyme that destroys the cell walls of bacteria. Phage lysin could be an alternative to conventional antibiotic therapy against pathogens that are resistant to multiple antibiotics. In this study, a novel staphylococcal phage, GH15, was isolated, and the endogenous lytic enzy...

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Autors principals: Gu, Jingmin, Xu, Wei, Lei, Liancheng, Huang, Jing, Feng, Xin, Sun, Changjiang, Du, Chongtao, Zuo, Jing, Li, Yang, Du, Taofeng, Li, Linxi, Han, Wenyu
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2011
Matèries:
Bacteriology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3020447/
https://ncbi.nlm.nih.gov/pubmed/21048011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.01144-10
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