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Defects in chromosome congression and mitotic progression in KIF18A-deficient cells are partly mediated through impaired functions of CENP-E

KIF18A, a molecular motor, is an essential component in the regulation of orderly chromosome congression by attenuation of the kinetochore oscillation amplitude at the midzone during mitosis in vertebrate cells. Here we report that KIF18A depletion resulted in mitotic arrest which was accompanied by...

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Detalhes bibliográficos
Main Authors: Huang, Ying, Yao, Yixin, Xu, Han-Zhang, Wang, Zhu-Gang, Lu, Luo, Dai, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3020402/
https://ncbi.nlm.nih.gov/pubmed/19625775
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